BDBM50254839 CHEMBL520933::N-(4,5-dichlorothiophen-2-ylsulfonyl)-2-(3-(quinolin-2-ylthio)-1H-indol-4-yloxy)acetamide

SMILES: Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4n3)c12

InChI Key: InChIKey=LCRCEEDFIKPZGH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50254839   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50254839 (CHEMBL520933 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4n3)c12 Show InChI InChI=1S/C23H15Cl2N3O4S3/c24-14-10-21(34-23(14)25)35(30,31)28-19(29)12-32-17-7-3-6-16-22(17)18(11-26-16)33-20-9-8-13-4-1-2-5-15(13)27-20/h1-11,26H,12H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50254839 (CHEMBL520933 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4n3)c12 Show InChI InChI=1S/C23H15Cl2N3O4S3/c24-14-10-21(34-23(14)25)35(30,31)28-19(29)12-32-17-7-3-6-16-22(17)18(11-26-16)33-20-9-8-13-4-1-2-5-15(13)27-20/h1-11,26H,12H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair