null

SMILES: C[C@H]1CN(Cc2ccc(cc2)-c2ccccc2C(=O)N2CCC(CC2)C(=O)c2ccc(F)cc2)C[C@@H](C)N1

InChI Key: InChIKey=FSYXVLMRBONNFA-ZRZAMGCNSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50254999   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50254999 (CHEMBL480210 | [4'-((3R,5S)-3,5-Dimethyl-piperazin...) Show SMILES C[C@H]1CN(Cc2ccc(cc2)-c2ccccc2C(=O)N2CCC(CC2)C(=O)c2ccc(F)cc2)C[C@@H](C)N1 |r| Show InChI InChI=1S/C32H36FN3O2/c1-22-19-35(20-23(2)34-22)21-24-7-9-25(10-8-24)29-5-3-4-6-30(29)32(38)36-17-15-27(16-18-36)31(37)26-11-13-28(33)14-12-26/h3-14,22-23,27,34H,15-21H2,1-2H3/t22-,23+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of CYP3A4 (unknown origin) using diethoxyfluorescein substrate				Bioorg Med Chem Lett 18: 6429-36 (2008) Article DOI: 10.1016/j.bmcl.2008.10.072 BindingDB Entry DOI: 10.7270/Q2HQ3ZR3
					More data for this Ligand-Target Pair
Motilin receptor (Homo sapiens (Human))	BDBM50254999 (CHEMBL480210 | [4'-((3R,5S)-3,5-Dimethyl-piperazin...) Show SMILES C[C@H]1CN(Cc2ccc(cc2)-c2ccccc2C(=O)N2CCC(CC2)C(=O)c2ccc(F)cc2)C[C@@H](C)N1 |r| Show InChI InChI=1S/C32H36FN3O2/c1-22-19-35(20-23(2)34-22)21-24-7-9-25(10-8-24)29-5-3-4-6-30(29)32(38)36-17-15-27(16-18-36)31(37)26-11-13-28(33)14-12-26/h3-14,22-23,27,34H,15-21H2,1-2H3/t22-,23+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	63.1	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assay				Bioorg Med Chem Lett 18: 6429-36 (2008) Article DOI: 10.1016/j.bmcl.2008.10.072 BindingDB Entry DOI: 10.7270/Q2HQ3ZR3
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50254999 (CHEMBL480210 | [4'-((3R,5S)-3,5-Dimethyl-piperazin...) Show SMILES C[C@H]1CN(Cc2ccc(cc2)-c2ccccc2C(=O)N2CCC(CC2)C(=O)c2ccc(F)cc2)C[C@@H](C)N1 |r| Show InChI InChI=1S/C32H36FN3O2/c1-22-19-35(20-23(2)34-22)21-24-7-9-25(10-8-24)29-5-3-4-6-30(29)32(38)36-17-15-27(16-18-36)31(37)26-11-13-28(33)14-12-26/h3-14,22-23,27,34H,15-21H2,1-2H3/t22-,23+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of CYP3A4 (unknown origin) using phenylpiperazinylmethylbenzylresofurin substrate				Bioorg Med Chem Lett 18: 6429-36 (2008) Article DOI: 10.1016/j.bmcl.2008.10.072 BindingDB Entry DOI: 10.7270/Q2HQ3ZR3
					More data for this Ligand-Target Pair