BDBM50255125 CHEMBL481823::N-(3,4-difluorophenylsulfonyl)-3-(1-(4-fluorobenzyl)-3a-methyl-2-oxo-2,3,3a,4,5,6-hexahydro-1H-indol-7-yl)acrylamide

SMILES: CC12CC(=O)N(Cc3ccc(F)cc3)C1=C(CCC2)\C=C\C(=O)NS(=O)(=O)c1ccc(F)c(F)c1

InChI Key: InChIKey=KWSLUGGHBJDVHK-IZZDOVSWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255125   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50255125 (CHEMBL481823 | N-(3,4-difluorophenylsulfonyl)-3-(1...) Show SMILES CC12CC(=O)N(Cc3ccc(F)cc3)C1=C(CCC2)\C=C\C(=O)NS(=O)(=O)c1ccc(F)c(F)c1 |c:16| Show InChI InChI=1S/C25H23F3N2O4S/c1-25-12-2-3-17(24(25)30(23(32)14-25)15-16-4-7-18(26)8-5-16)6-11-22(31)29-35(33,34)19-9-10-20(27)21(28)13-19/h4-11,13H,2-3,12,14-15H2,1H3,(H,29,31)/b11-6+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 778-82 (2009) Article DOI: 10.1016/j.bmcl.2008.12.027 BindingDB Entry DOI: 10.7270/Q24M94DH
					More data for this Ligand-Target Pair