BDBM50255159 CHEMBL515569::N-{(1R,2S,5S)-2-{[(5-Chloroindol-2-yl)carbonyl]amino}-5-[ethyl(methyl)carbamoyl]cyclohexyl}-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide

SMILES: CCN(C)C(=O)[C@H]1CC[C@H](NC(=O)c2cc3cc(Cl)ccc3[nH]2)[C@@H](C1)NC(=O)c1nc2CCN(C)Cc2s1

InChI Key: InChIKey=UPOAXARIYGASML-PAXLWEDBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255159   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50255159 (CHEMBL515569 | N-{(1R,2S,5S)-2-{[(5-Chloroindol-2-...) Show SMILES CCN(C)C(=O)[C@H]1CC[C@H](NC(=O)c2cc3cc(Cl)ccc3[nH]2)[C@@H](C1)NC(=O)c1nc2CCN(C)Cc2s1 |r| Show InChI InChI=1S/C27H33ClN6O3S/c1-4-34(3)27(37)15-5-7-19(30-24(35)22-13-16-11-17(28)6-8-18(16)29-22)21(12-15)31-25(36)26-32-20-9-10-33(2)14-23(20)38-26/h6,8,11,13,15,19,21,29H,4-5,7,9-10,12,14H2,1-3H3,(H,30,35)(H,31,36)/t15-,19-,21+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem 17: 1193-206 (2009) Article DOI: 10.1016/j.bmc.2008.12.037 BindingDB Entry DOI: 10.7270/Q2V69JGR
					More data for this Ligand-Target Pair