BDBM50255204 CHEMBL515895::N-[(1R,2S,5S)-2-{[(5-Chloroindol-2-yl)carbonyl]amino}-5-(diethylcarbamoyl)cyclohexyl]-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide

SMILES: CCN(CC)C(=O)[C@H]1CC[C@H](NC(=O)c2cc3cc(Cl)ccc3[nH]2)[C@@H](C1)NC(=O)c1nc2CCN(C)Cc2s1

InChI Key: InChIKey=MWLXGKYGQNJGCE-XUEUYAKLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255204   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50255204 (CHEMBL515895 | N-[(1R,2S,5S)-2-{[(5-Chloroindol-2-...) Show SMILES CCN(CC)C(=O)[C@H]1CC[C@H](NC(=O)c2cc3cc(Cl)ccc3[nH]2)[C@@H](C1)NC(=O)c1nc2CCN(C)Cc2s1 |r| Show InChI InChI=1S/C28H35ClN6O3S/c1-4-35(5-2)28(38)16-6-8-20(31-25(36)23-14-17-12-18(29)7-9-19(17)30-23)22(13-16)32-26(37)27-33-21-10-11-34(3)15-24(21)39-27/h7,9,12,14,16,20,22,30H,4-6,8,10-11,13,15H2,1-3H3,(H,31,36)(H,32,37)/t16-,20-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem 17: 1193-206 (2009) Article DOI: 10.1016/j.bmc.2008.12.037 BindingDB Entry DOI: 10.7270/Q2V69JGR
					More data for this Ligand-Target Pair