BDBM50255219 (+/-)-benzyl-3-(4-(methylthio)benzamido)-4-(2-(3-(trifluoromethyl)benzamido)acetamido)cyclohexylcarbamate::(+/-)-benzyl3-(4-(methylthio)benzamido)-4-( 2-(3-(trifluoromethyl)benzamido)acetamido)cyclohexylcarbamate::CHEMBL505722

SMILES: CSc1ccc(cc1)C(=O)NC1CC(CCC1NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)NC(=O)OCc1ccccc1

InChI Key: InChIKey=LAPGFBUSBADRJT-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50255219   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50255219 ((+/-)-benzyl-3-(4-(methylthio)benzamido)-4-(2-(3-(...) Show SMILES CSc1ccc(cc1)C(=O)NC1CC(CCC1NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C32H33F3N4O5S/c1-45-25-13-10-21(11-14-25)30(42)39-27-17-24(37-31(43)44-19-20-6-3-2-4-7-20)12-15-26(27)38-28(40)18-36-29(41)22-8-5-9-23(16-22)32(33,34)35/h2-11,13-14,16,24,26-27H,12,15,17-19H2,1H3,(H,36,41)(H,37,43)(H,38,40)(H,39,42)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Antagonist activity at CCR2 in human monocytes assessed as inhibition of MCP1-induced calcium influx by FLIPR				Bioorg Med Chem Lett 19: 597-601 (2009) Article DOI: 10.1016/j.bmcl.2008.12.062 BindingDB Entry DOI: 10.7270/Q2QF8SR1
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50255219 ((+/-)-benzyl-3-(4-(methylthio)benzamido)-4-(2-(3-(...) Show SMILES CSc1ccc(cc1)C(=O)NC1CC(CCC1NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C32H33F3N4O5S/c1-45-25-13-10-21(11-14-25)30(42)39-27-17-24(37-31(43)44-19-20-6-3-2-4-7-20)12-15-26(27)38-28(40)18-36-29(41)22-8-5-9-23(16-22)32(33,34)35/h2-11,13-14,16,24,26-27H,12,15,17-19H2,1H3,(H,36,41)(H,37,43)(H,38,40)(H,39,42)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125I]MCP1 from CCR2 in human PBMCs				Bioorg Med Chem Lett 19: 597-601 (2009) Article DOI: 10.1016/j.bmcl.2008.12.062 BindingDB Entry DOI: 10.7270/Q2QF8SR1
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50255219 ((+/-)-benzyl-3-(4-(methylthio)benzamido)-4-(2-(3-(...) Show SMILES CSc1ccc(cc1)C(=O)NC1CC(CCC1NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C32H33F3N4O5S/c1-45-25-13-10-21(11-14-25)30(42)39-27-17-24(37-31(43)44-19-20-6-3-2-4-7-20)12-15-26(27)38-28(40)18-36-29(41)22-8-5-9-23(16-22)32(33,34)35/h2-11,13-14,16,24,26-27H,12,15,17-19H2,1H3,(H,36,41)(H,37,43)(H,38,40)(H,39,42)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of CCR3 (unknown origin) at 10 uM				Bioorg Med Chem Lett 19: 597-601 (2009) Article DOI: 10.1016/j.bmcl.2008.12.062 BindingDB Entry DOI: 10.7270/Q2QF8SR1
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50255219 ((+/-)-benzyl-3-(4-(methylthio)benzamido)-4-(2-(3-(...) Show SMILES CSc1ccc(cc1)C(=O)NC1CC(CCC1NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C32H33F3N4O5S/c1-45-25-13-10-21(11-14-25)30(42)39-27-17-24(37-31(43)44-19-20-6-3-2-4-7-20)12-15-26(27)38-28(40)18-36-29(41)22-8-5-9-23(16-22)32(33,34)35/h2-11,13-14,16,24,26-27H,12,15,17-19H2,1H3,(H,36,41)(H,37,43)(H,38,40)(H,39,42)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Antagonist activity at CCR2 in human PBMCs assessed as inhibition of MCP1-induced chemotaxis				Bioorg Med Chem Lett 19: 597-601 (2009) Article DOI: 10.1016/j.bmcl.2008.12.062 BindingDB Entry DOI: 10.7270/Q2QF8SR1
					More data for this Ligand-Target Pair