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BDBM50255229 CHEMBL482207::N-(4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin-6-yl)-1H-imidazol-2-yl)isobutyramide

SMILES: CC(C)C(=O)Nc1nc(c([nH]1)-c1ccc2nccnc2c1)-c1ccc(F)c(C)n1

InChI Key: InChIKey=AKXGHZQCJYYVLK-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255229   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
TGF-beta receptor type I


(Homo sapiens (Human))
BDBM50255229
PNG
(CHEMBL482207 | N-(4-(5-fluoro-6-methylpyridin-2-yl...)
Show SMILES CC(C)C(=O)Nc1nc(c([nH]1)-c1ccc2nccnc2c1)-c1ccc(F)c(C)n1
Show InChI InChI=1S/C21H19FN6O/c1-11(2)20(29)28-21-26-18(13-4-6-15-17(10-13)24-9-8-23-15)19(27-21)16-7-5-14(22)12(3)25-16/h4-11H,1-3H3,(H2,26,27,28,29)
PDB

KEGG

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>2.80E+4n/an/an/an/an/an/an/an/a



Abbot Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human TGFBR1


Bioorg Med Chem Lett 19: 912-6 (2009)


Article DOI: 10.1016/j.bmcl.2008.11.119
More data for this
Ligand-Target Pair