null

SMILES: CC(C)(C)[C@H]1CC[C@@H](CC1)NC(=O)N1CCC2(CC1)[C@@H](N(C2=O)c1ccccc1)c1ccccc1

InChI Key: InChIKey=BVDKYCVYZYRHCB-GNKBHMEESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50255382   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50255382 ((S)-N-((1r,4S)-4-tert-butylcyclohexyl)-1-oxo-2,3-d...) Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)NC(=O)N1CCC2(CC1)[C@@H](N(C2=O)c1ccccc1)c1ccccc1 |r,wU:4.3,19.32,wD:7.10,(30.29,-16.11,;28.97,-15.34,;28.2,-16.68,;29.75,-14.01,;27.63,-14.57,;26.3,-15.34,;24.97,-14.57,;24.97,-13.03,;26.3,-12.26,;27.63,-13.03,;23.64,-12.26,;22.31,-13.03,;22.31,-14.57,;20.97,-12.26,;19.65,-13.02,;18.32,-12.26,;18.31,-10.71,;19.65,-9.94,;20.97,-10.72,;17.54,-9.38,;16.2,-10.15,;16.98,-11.49,;16.58,-12.98,;14.71,-9.77,;14.31,-8.28,;12.83,-7.88,;11.74,-8.98,;12.15,-10.47,;13.63,-10.86,;17.93,-7.89,;19.42,-7.49,;19.81,-6,;18.72,-4.92,;17.23,-5.33,;16.84,-6.81,)| Show InChI InChI=1S/C30H39N3O2/c1-29(2,3)23-14-16-24(17-15-23)31-28(35)32-20-18-30(19-21-32)26(22-10-6-4-7-11-22)33(27(30)34)25-12-8-5-9-13-25/h4-13,23-24,26H,14-21H2,1-3H3,(H,31,35)/t23-,24-,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Antagonist activity at TRPV1 (unknown origin) expressed in HEK293 cells assessed as inhibition of capsaicin-induced activation by FLIPR assay				Bioorg Med Chem Lett 19: 783-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.024 BindingDB Entry DOI: 10.7270/Q2F47P1D
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50255382 ((S)-N-((1r,4S)-4-tert-butylcyclohexyl)-1-oxo-2,3-d...) Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)NC(=O)N1CCC2(CC1)[C@@H](N(C2=O)c1ccccc1)c1ccccc1 |r,wU:4.3,19.32,wD:7.10,(30.29,-16.11,;28.97,-15.34,;28.2,-16.68,;29.75,-14.01,;27.63,-14.57,;26.3,-15.34,;24.97,-14.57,;24.97,-13.03,;26.3,-12.26,;27.63,-13.03,;23.64,-12.26,;22.31,-13.03,;22.31,-14.57,;20.97,-12.26,;19.65,-13.02,;18.32,-12.26,;18.31,-10.71,;19.65,-9.94,;20.97,-10.72,;17.54,-9.38,;16.2,-10.15,;16.98,-11.49,;16.58,-12.98,;14.71,-9.77,;14.31,-8.28,;12.83,-7.88,;11.74,-8.98,;12.15,-10.47,;13.63,-10.86,;17.93,-7.89,;19.42,-7.49,;19.81,-6,;18.72,-4.92,;17.23,-5.33,;16.84,-6.81,)| Show InChI InChI=1S/C30H39N3O2/c1-29(2,3)23-14-16-24(17-15-23)31-28(35)32-20-18-30(19-21-32)26(22-10-6-4-7-11-22)33(27(30)34)25-12-8-5-9-13-25/h4-13,23-24,26H,14-21H2,1-3H3,(H,31,35)/t23-,24-,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Antagonist activity at TRPV1 expressed in HEK293 cells assessed as inhibition of PMA-induced activation by FLIPR assay				Bioorg Med Chem Lett 19: 783-7 (2009) Article DOI: 10.1016/j.bmcl.2008.12.024 BindingDB Entry DOI: 10.7270/Q2F47P1D
					More data for this Ligand-Target Pair