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SMILES: CN1CCN(CC1)c1cc2c(Nc3cccc(Cl)c3Cl)c(cnc2cc1F)C(N)=O

InChI Key: InChIKey=NEPZSLDMGYMYSA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255594   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))		BDBM50255594
PNG
(4-(2,3-dichlorophenylamino)-7-fluoro-6-(4-methylpi...)
Show SMILES CN1CCN(CC1)c1cc2c(Nc3cccc(Cl)c3Cl)c(cnc2cc1F)C(N)=O
Show InChI InChI=1S/C21H20Cl2FN5O/c1-28-5-7-29(8-6-28)18-9-12-17(10-15(18)24)26-11-13(21(25)30)20(12)27-16-4-2-3-14(22)19(16)23/h2-4,9-11H,5-8H2,1H3,(H2,25,30)(H,26,27)
PDB

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Similars
Article
PubMed
n/an/a 3n/an/an/an/an/an/a



AstraZeneca R&D Boston

Curated by ChEMBL


Assay Description
Inhibition of CSF1R (unknown origin)

Bioorg Med Chem Lett 19: 701-5 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.044
BindingDB Entry DOI: 10.7270/Q2JW8DSV
More data for this
Ligand-Target Pair