BDBM50255697 4-(2,3-dichlorophenylamino)-6-(2-(dimethylamino)ethylamino)-7-ethoxyquinoline-3-carboxamide::CHEMBL480814

SMILES: CCOc1cc2ncc(C(N)=O)c(Nc3cccc(Cl)c3Cl)c2cc1NCCN(C)C

InChI Key: InChIKey=HXFQPJSSCJUGEN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255697   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50255697 (4-(2,3-dichlorophenylamino)-6-(2-(dimethylamino)et...) Show SMILES CCOc1cc2ncc(C(N)=O)c(Nc3cccc(Cl)c3Cl)c2cc1NCCN(C)C Show InChI InChI=1S/C22H25Cl2N5O2/c1-4-31-19-11-17-13(10-18(19)26-8-9-29(2)3)21(14(12-27-17)22(25)30)28-16-7-5-6-15(23)20(16)24/h5-7,10-12,26H,4,8-9H2,1-3H3,(H2,25,30)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Boston Curated by ChEMBL					Assay Description Inhibition of His-tagged CSF1R catalytic domain (unknown origin) expressed in baculovirus by HTRF assay				Bioorg Med Chem Lett 19: 697-700 (2009) Article DOI: 10.1016/j.bmcl.2008.12.046 BindingDB Entry DOI: 10.7270/Q26M36P8
					More data for this Ligand-Target Pair