BDBM50255795 1-[(Benzyl-methyl-amino)-methyl]-8,9-dihydro-7H-2,7,9a-triaza-benzo[cd]azulen-6-one::CHEMBL519778

SMILES: CN(Cc1nc2cccc3C(=O)NCCn1c23)Cc1ccccc1

InChI Key: InChIKey=YIVDMZRTALDUMH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50255795   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50255795 (1-[(Benzyl-methyl-amino)-methyl]-8,9-dihydro-7H-2,...) Show SMILES CN(Cc1nc2cccc3C(=O)NCCn1c23)Cc1ccccc1 Show InChI InChI=1S/C19H20N4O/c1-22(12-14-6-3-2-4-7-14)13-17-21-16-9-5-8-15-18(16)23(17)11-10-20-19(15)24/h2-9H,10-13H2,1H3,(H,20,24)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Huazhong University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human recombinant PARP1				J Med Chem 52: 718-25 (2009) Article DOI: 10.1021/jm800902t BindingDB Entry DOI: 10.7270/Q2C53KPW
					More data for this Ligand-Target Pair