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SMILES: NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3c(Cl)c(Cl)sc3c12

InChI Key: InChIKey=ZUYQREXPBSBKHP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50256001   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))		BDBM50256001
PNG
(4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]...)
Show SMILES NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3c(Cl)c(Cl)sc3c12 |w:3.2,t:1|
Show InChI InChI=1S/C13H9Cl2N5O2S/c14-5-8-9(23-10(5)15)4-3(6-12(22)20-13(16)19-6)1-2-17-11(21)7(4)18-8/h18H,1-2H2,(H,17,21)(H3,16,19,20,22)
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Similars
Article
PubMed
n/an/a 890n/an/an/an/an/an/a



Institut de Recherche Servier

Curated by ChEMBL


Assay Description
Inhibition of CHK1

Bioorg Med Chem Lett 19: 841-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.001
BindingDB Entry DOI: 10.7270/Q2QN66MH
More data for this
Ligand-Target Pair