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SMILES: NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3c(csc3c12)C#N

InChI Key: InChIKey=DFOZXVZCZUBSOR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50256004   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))		BDBM50256004
PNG
(4-[2-Amino-5-oxo-3,5-dihydro-imidazol-(4)-ylidene]...)
Show SMILES NC1=NC(C(=O)N1)=C1CCNC(=O)c2[nH]c3c(csc3c12)C#N |w:3.2,t:1|
Show InChI InChI=1S/C14H10N6O2S/c15-3-5-4-23-11-7-6(9-13(22)20-14(16)19-9)1-2-17-12(21)10(7)18-8(5)11/h4,18H,1-2H2,(H,17,21)(H3,16,19,20,22)
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Similars
Article
PubMed
n/an/a 29n/an/an/an/an/an/a



Institut de Recherche Servier

Curated by ChEMBL


Assay Description
Inhibition of CHK1

Bioorg Med Chem Lett 19: 841-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.001
BindingDB Entry DOI: 10.7270/Q2QN66MH
More data for this
Ligand-Target Pair