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SMILES: NC1=NC(=O)C(S1)=C1CCNC(=O)c2[nH]c3c(Br)csc3c12

InChI Key: InChIKey=MUNASHRNFSWBGX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50256029   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase Chk1


(Homo sapiens (Human))		BDBM50256029
PNG
(4-[2-Amino-4-oxo-4H-thiazol-(5)-ylidene]-1-bromo-4...)
Show SMILES NC1=NC(=O)C(S1)=C1CCNC(=O)c2[nH]c3c(Br)csc3c12 |w:5.5,t:1|
Show InChI InChI=1S/C13H9BrN4O2S2/c14-5-3-21-10-6-4(9-12(20)18-13(15)22-9)1-2-16-11(19)8(6)17-7(5)10/h3,17H,1-2H2,(H,16,19)(H2,15,18,20)
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Similars
Article
PubMed
n/an/a 190n/an/an/an/an/an/a



Institut de Recherche Servier

Curated by ChEMBL


Assay Description
Inhibition of CHK1

Bioorg Med Chem Lett 19: 841-4 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.001
BindingDB Entry DOI: 10.7270/Q2QN66MH
More data for this
Ligand-Target Pair