BDBM50256751 CHEMBL514670::N-(6-amino-5-chloropyridin-3-yl)-2-methyl-5-(3-(trifluoromethyl)benzamido)benzamide

SMILES: Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1C(=O)Nc1cnc(N)c(Cl)c1

InChI Key: InChIKey=BYCBVTAUYYXCCF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50256751   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50256751 (CHEMBL514670 | N-(6-amino-5-chloropyridin-3-yl)-2-...) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1C(=O)Nc1cnc(N)c(Cl)c1 Show InChI InChI=1S/C21H16ClF3N4O2/c1-11-5-6-14(28-19(30)12-3-2-4-13(7-12)21(23,24)25)8-16(11)20(31)29-15-9-17(22)18(26)27-10-15/h2-10H,1H3,(H2,26,27)(H,28,30)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Boston Curated by ChEMBL					Assay Description Inhibition of CYP2C9 (unknown origin)				Bioorg Med Chem Lett 19: 1026-9 (2009) Article DOI: 10.1016/j.bmcl.2008.10.053 BindingDB Entry DOI: 10.7270/Q2222TMP
					More data for this Ligand-Target Pair