null

SMILES: Cc1ccc(NC(=O)c2ccc(s2)C(=O)Nc2ccccc2N)cc1Nc1ncc(cn1)-c1cccnc1

InChI Key: InChIKey=WSOUPZRFRJNSQF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50257030   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50257030 (CHEMBL473825 | N2-(2-aminophenyl)-N5-(4-methyl-3-(...) Show SMILES Cc1ccc(NC(=O)c2ccc(s2)C(=O)Nc2ccccc2N)cc1Nc1ncc(cn1)-c1cccnc1 Show InChI InChI=1S/C28H23N7O2S/c1-17-8-9-20(13-23(17)35-28-31-15-19(16-32-28)18-5-4-12-30-14-18)33-26(36)24-10-11-25(38-24)27(37)34-22-7-3-2-6-21(22)29/h2-16H,29H2,1H3,(H,33,36)(H,34,37)(H,31,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of wild-type c-Abl (unknown origin) by liquid scintillation counting				J Med Chem 52: 2265-79 (2009) Article DOI: 10.1021/jm800988r BindingDB Entry DOI: 10.7270/Q2NS0TSP
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50257030 (CHEMBL473825 | N2-(2-aminophenyl)-N5-(4-methyl-3-(...) Show SMILES Cc1ccc(NC(=O)c2ccc(s2)C(=O)Nc2ccccc2N)cc1Nc1ncc(cn1)-c1cccnc1 Show InChI InChI=1S/C28H23N7O2S/c1-17-8-9-20(13-23(17)35-28-31-15-19(16-32-28)18-5-4-12-30-14-18)33-26(36)24-10-11-25(38-24)27(37)34-22-7-3-2-6-21(22)29/h2-16H,29H2,1H3,(H,33,36)(H,34,37)(H,31,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC1 expressed in HEK293 cells				J Med Chem 52: 2265-79 (2009) Article DOI: 10.1021/jm800988r BindingDB Entry DOI: 10.7270/Q2NS0TSP
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50257030 (CHEMBL473825 | N2-(2-aminophenyl)-N5-(4-methyl-3-(...) Show SMILES Cc1ccc(NC(=O)c2ccc(s2)C(=O)Nc2ccccc2N)cc1Nc1ncc(cn1)-c1cccnc1 Show InChI InChI=1S/C28H23N7O2S/c1-17-8-9-20(13-23(17)35-28-31-15-19(16-32-28)18-5-4-12-30-14-18)33-26(36)24-10-11-25(38-24)27(37)34-22-7-3-2-6-21(22)29/h2-16H,29H2,1H3,(H,33,36)(H,34,37)(H,31,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta (unknown origin) by liquid scintillation counting				J Med Chem 52: 2265-79 (2009) Article DOI: 10.1021/jm800988r BindingDB Entry DOI: 10.7270/Q2NS0TSP
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50257030 (CHEMBL473825 | N2-(2-aminophenyl)-N5-(4-methyl-3-(...) Show SMILES Cc1ccc(NC(=O)c2ccc(s2)C(=O)Nc2ccccc2N)cc1Nc1ncc(cn1)-c1cccnc1 Show InChI InChI=1S/C28H23N7O2S/c1-17-8-9-20(13-23(17)35-28-31-15-19(16-32-28)18-5-4-12-30-14-18)33-26(36)24-10-11-25(38-24)27(37)34-22-7-3-2-6-21(22)29/h2-16H,29H2,1H3,(H,33,36)(H,34,37)(H,31,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of human recombinant HDAC6 expressed in HEK293 cells				J Med Chem 52: 2265-79 (2009) Article DOI: 10.1021/jm800988r BindingDB Entry DOI: 10.7270/Q2NS0TSP
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50257030 (CHEMBL473825 | N2-(2-aminophenyl)-N5-(4-methyl-3-(...) Show SMILES Cc1ccc(NC(=O)c2ccc(s2)C(=O)Nc2ccccc2N)cc1Nc1ncc(cn1)-c1cccnc1 Show InChI InChI=1S/C28H23N7O2S/c1-17-8-9-20(13-23(17)35-28-31-15-19(16-32-28)18-5-4-12-30-14-18)33-26(36)24-10-11-25(38-24)27(37)34-22-7-3-2-6-21(22)29/h2-16H,29H2,1H3,(H,33,36)(H,34,37)(H,31,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) by liquid scintillation counting				J Med Chem 52: 2265-79 (2009) Article DOI: 10.1021/jm800988r BindingDB Entry DOI: 10.7270/Q2NS0TSP
					More data for this Ligand-Target Pair