BDBM50257540 (S)-N-(1-(4-(5-bromo-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)propan-2-yl)-4-chlorobenzamide::CHEMBL523011

SMILES: C[C@@H](CN1CCC(CC1)n1c2ccc(Br)cc2[nH]c1=O)NC(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=BSGGZEUVJPHPOY-AWEZNQCLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase D (PLD) (Homo sapiens (Human))	BDBM50257540 ((S)-N-(1-(4-(5-bromo-2-oxo-2,3-dihydro-1H-benzo[d]...) Show SMILES C[C@@H](CN1CCC(CC1)n1c2ccc(Br)cc2[nH]c1=O)NC(=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C22H24BrClN4O2/c1-14(25-21(29)15-2-5-17(24)6-3-15)13-27-10-8-18(9-11-27)28-20-7-4-16(23)12-19(20)26-22(28)30/h2-7,12,14,18H,8-11,13H2,1H3,(H,25,29)(H,26,30)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of human PLD1 in Calu1 cells				Bioorg Med Chem Lett 19: 1916-20 (2009) Article DOI: 10.1016/j.bmcl.2009.02.057 BindingDB Entry DOI: 10.7270/Q2VM4C5W
					More data for this Ligand-Target Pair
Phospholipase D2 (PLD2) (Homo sapiens (Human))	BDBM50257540 ((S)-N-(1-(4-(5-bromo-2-oxo-2,3-dihydro-1H-benzo[d]...) Show SMILES C[C@@H](CN1CCC(CC1)n1c2ccc(Br)cc2[nH]c1=O)NC(=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C22H24BrClN4O2/c1-14(25-21(29)15-2-5-17(24)6-3-15)13-27-10-8-18(9-11-27)28-20-7-4-16(23)12-19(20)26-22(28)30/h2-7,12,14,18H,8-11,13H2,1H3,(H,25,29)(H,26,30)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of GFP-labelled human PLD2 HEK293 cells				Bioorg Med Chem Lett 19: 1916-20 (2009) Article DOI: 10.1016/j.bmcl.2009.02.057 BindingDB Entry DOI: 10.7270/Q2VM4C5W
					More data for this Ligand-Target Pair