BDBM50258053 CHEMBL492568::N-(biphenyl-4-yl)-1-(methylsulfonyl)spiro[indoline-3,4'-piperidine]-1'-carboxamide

SMILES: CS(=O)(=O)N1CC2(CCN(CC2)C(=O)Nc2ccc(cc2)-c2ccccc2)c2ccccc12

InChI Key: InChIKey=HXFXDYHBJKXSJH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human))	BDBM50258053 (CHEMBL492568 | N-(biphenyl-4-yl)-1-(methylsulfonyl...) Show SMILES CS(=O)(=O)N1CC2(CCN(CC2)C(=O)Nc2ccc(cc2)-c2ccccc2)c2ccccc12 Show InChI InChI=1S/C26H27N3O3S/c1-33(31,32)29-19-26(23-9-5-6-10-24(23)29)15-17-28(18-16-26)25(30)27-22-13-11-21(12-14-22)20-7-3-2-4-8-20/h2-14H,15-19H2,1H3,(H,27,30)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.850	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human recombinant Y5 receptor expressed in mouse LMtk cells				Bioorg Med Chem Lett 19: 1564-8 (2009) Article DOI: 10.1016/j.bmcl.2009.02.035 BindingDB Entry DOI: 10.7270/Q2TQ61FT
					More data for this Ligand-Target Pair