BDBM50258158 2-(4-tert-butylphenyl)-4-(4-((1,3-dimethyl-1H-pyrazol-5-yl)methyl)piperazin-1-yl)-1H-benzo[d]imidazole::CHEMBL522202

SMILES: Cc1cc(CN2CCN(CC2)c2cccc3[nH]c(nc23)-c2ccc(cc2)C(C)(C)C)n(C)n1

InChI Key: InChIKey=PVFARRTWKHNJLR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin releasing hormone 1 (GnRHR1) (Homo sapiens (Human))	BDBM50258158 (2-(4-tert-butylphenyl)-4-(4-((1,3-dimethyl-1H-pyra...) Show SMILES Cc1cc(CN2CCN(CC2)c2cccc3[nH]c(nc23)-c2ccc(cc2)C(C)(C)C)n(C)n1 Show InChI InChI=1S/C27H34N6/c1-19-17-22(31(5)30-19)18-32-13-15-33(16-14-32)24-8-6-7-23-25(24)29-26(28-23)20-9-11-21(12-10-20)27(2,3)4/h6-12,17H,13-16,18H2,1-5H3,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [125I]-(D-Trp6)-GnRH from human GnRH receptor				Bioorg Med Chem Lett 19: 1986-90 (2009) Article DOI: 10.1016/j.bmcl.2009.02.043 BindingDB Entry DOI: 10.7270/Q28S4PS4
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50258158 (2-(4-tert-butylphenyl)-4-(4-((1,3-dimethyl-1H-pyra...) Show SMILES Cc1cc(CN2CCN(CC2)c2cccc3[nH]c(nc23)-c2ccc(cc2)C(C)(C)C)n(C)n1 Show InChI InChI=1S/C27H34N6/c1-19-17-22(31(5)30-19)18-32-13-15-33(16-14-32)24-8-6-7-23-25(24)29-26(28-23)20-9-11-21(12-10-20)27(2,3)4/h6-12,17H,13-16,18H2,1-5H3,(H,28,29)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [125I]-(D-Trp6)-GnRH from rat GnRH receptor				Bioorg Med Chem Lett 19: 1986-90 (2009) Article DOI: 10.1016/j.bmcl.2009.02.043 BindingDB Entry DOI: 10.7270/Q28S4PS4
					More data for this Ligand-Target Pair