BDBM50258315 (+/-)-N-(3-(3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)-2-(3,4-difluorophenyl)-N-methyl-2-phenylacetamide::CHEMBL494016

SMILES: CN(CCCN1CCC2(CC1)OCc1ccccc21)C(=O)C(c1ccccc1)c1ccc(F)c(F)c1

InChI Key: InChIKey=IOVSXXYNGKBAID-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258315   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258315 ((+/-)-N-(3-(3H-spiro[isobenzofuran-1,4'-piperidine...) Show SMILES CN(CCCN1CCC2(CC1)OCc1ccccc21)C(=O)C(c1ccccc1)c1ccc(F)c(F)c1 Show InChI InChI=1S/C30H32F2N2O2/c1-33(29(35)28(22-8-3-2-4-9-22)23-12-13-26(31)27(32)20-23)16-7-17-34-18-14-30(15-19-34)25-11-6-5-10-24(25)21-36-30/h2-6,8-13,20,28H,7,14-19,21H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from human adrenergic alpha1A receptor expressed in thymidine kinase-deficient mouse LM cells				Bioorg Med Chem Lett 19: 3072-7 (2009) Article DOI: 10.1016/j.bmcl.2009.04.016 BindingDB Entry DOI: 10.7270/Q2668D3W
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50258315 ((+/-)-N-(3-(3H-spiro[isobenzofuran-1,4'-piperidine...) Show SMILES CN(CCCN1CCC2(CC1)OCc1ccccc21)C(=O)C(c1ccccc1)c1ccc(F)c(F)c1 Show InChI InChI=1S/C30H32F2N2O2/c1-33(29(35)28(22-8-3-2-4-9-22)23-12-13-26(31)27(32)20-23)16-7-17-34-18-14-30(15-19-34)25-11-6-5-10-24(25)21-36-30/h2-6,8-13,20,28H,7,14-19,21H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human MCHR1 expressed in CHO cells				Bioorg Med Chem Lett 19: 3072-7 (2009) Article DOI: 10.1016/j.bmcl.2009.04.016 BindingDB Entry DOI: 10.7270/Q2668D3W
					More data for this Ligand-Target Pair