BDBM50258390 4-(1H-indol-4-ylamino)-5-(4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)nicotinonitrile::CHEMBL493987
SMILES: CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2cccc3[nH]ccc23)CC1
InChI Key: InChIKey=ZPKBYERIJJCKAI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50258390 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein kinase C delta type
(Homo sapiens (Human)) | BDBM50258390
(4-(1H-indol-4-ylamino)-5-(4-(2-(4-methylpiperazin-...)Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2cccc3[nH]ccc23)CC1 Show InChI InChI=1S/C27H28N6O/c1-32-11-13-33(14-12-32)15-16-34-22-7-5-20(6-8-22)24-19-29-18-21(17-28)27(24)31-26-4-2-3-25-23(26)9-10-30-25/h2-10,18-19,30H,11-16H2,1H3,(H,29,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human PKCdelta by IMAP assay |
Bioorg Med Chem Lett 19: 3623-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.126
BindingDB Entry DOI: 10.7270/Q29W0FD4 |
More data for this
Ligand-Target Pair | |
Protein kinase C theta type
(Homo sapiens (Human)) | BDBM50258390
(4-(1H-indol-4-ylamino)-5-(4-(2-(4-methylpiperazin-...)Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2cccc3[nH]ccc23)CC1 Show InChI InChI=1S/C27H28N6O/c1-32-11-13-33(14-12-32)15-16-34-22-7-5-20(6-8-22)24-19-29-18-21(17-28)27(24)31-26-4-2-3-25-23(26)9-10-30-25/h2-10,18-19,30H,11-16H2,1H3,(H,29,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human PKCtheta by IMAP assay |
Bioorg Med Chem Lett 19: 3623-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.126
BindingDB Entry DOI: 10.7270/Q29W0FD4 |
More data for this
Ligand-Target Pair | |
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