BDBM50258489 CHEMBL4087852

SMILES: Fc1cccc(c1)S(=O)(=O)NCCCCN1CCC(=CC1)c1c[nH]c2ccc(Cl)cc12

InChI Key: InChIKey=QPXZVVCTRSBLHN-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50258489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50258489 (CHEMBL4087852) Show SMILES Fc1cccc(c1)S(=O)(=O)NCCCCN1CCC(=CC1)c1c[nH]c2ccc(Cl)cc12 |c:19| Show InChI InChI=1S/C23H25ClFN3O2S/c24-18-6-7-23-21(14-18)22(16-26-23)17-8-12-28(13-9-17)11-2-1-10-27-31(29,30)20-5-3-4-19(25)15-20/h3-8,14-16,26-27H,1-2,9-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Faculty of Pharmacy, Jagiellonian University Medical College , 9 Medyczna Street, 30-688 Kraków, Poland. Curated by ChEMBL					Assay Description Displacement of [3H]-methylspiperone from human D2 receptor expressed in CHO-K1 cells after 60 mins by scintillation counting				J Med Chem 60: 7483-7501 (2017) Article DOI: 10.1021/acs.jmedchem.7b00839 BindingDB Entry DOI: 10.7270/Q2K939ZD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50258489 (CHEMBL4087852) Show SMILES Fc1cccc(c1)S(=O)(=O)NCCCCN1CCC(=CC1)c1c[nH]c2ccc(Cl)cc12 |c:19| Show InChI InChI=1S/C23H25ClFN3O2S/c24-18-6-7-23-21(14-18)22(16-26-23)17-8-12-28(13-9-17)11-2-1-10-27-31(29,30)20-5-3-4-19(25)15-20/h3-8,14-16,26-27H,1-2,9-13H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Faculty of Pharmacy, Jagiellonian University Medical College , 9 Medyczna Street, 30-688 Kraków, Poland. Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 60: 7483-7501 (2017) Article DOI: 10.1021/acs.jmedchem.7b00839 BindingDB Entry DOI: 10.7270/Q2K939ZD
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50258489 (CHEMBL4087852) Show SMILES Fc1cccc(c1)S(=O)(=O)NCCCCN1CCC(=CC1)c1c[nH]c2ccc(Cl)cc12 |c:19| Show InChI InChI=1S/C23H25ClFN3O2S/c24-18-6-7-23-21(14-18)22(16-26-23)17-8-12-28(13-9-17)11-2-1-10-27-31(29,30)20-5-3-4-19(25)15-20/h3-8,14-16,26-27H,1-2,9-13H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Faculty of Pharmacy, Jagiellonian University Medical College , 9 Medyczna Street, 30-688 Kraków, Poland. Curated by ChEMBL					Assay Description Displacement of [3H]-imipramine from human serotonin transporter expressed in HEK-293 cell membranes after 30 mins by scintillation counting				J Med Chem 60: 7483-7501 (2017) Article DOI: 10.1021/acs.jmedchem.7b00839 BindingDB Entry DOI: 10.7270/Q2K939ZD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50258489 (CHEMBL4087852) Show SMILES Fc1cccc(c1)S(=O)(=O)NCCCCN1CCC(=CC1)c1c[nH]c2ccc(Cl)cc12 |c:19| Show InChI InChI=1S/C23H25ClFN3O2S/c24-18-6-7-23-21(14-18)22(16-26-23)17-8-12-28(13-9-17)11-2-1-10-27-31(29,30)20-5-3-4-19(25)15-20/h3-8,14-16,26-27H,1-2,9-13H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Faculty of Pharmacy, Jagiellonian University Medical College , 9 Medyczna Street, 30-688 Kraków, Poland. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT7 receptor expressed in CHO-K1 cell membranes after 120 mins by scintillation counting				J Med Chem 60: 7483-7501 (2017) Article DOI: 10.1021/acs.jmedchem.7b00839 BindingDB Entry DOI: 10.7270/Q2K939ZD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50258489 (CHEMBL4087852) Show SMILES Fc1cccc(c1)S(=O)(=O)NCCCCN1CCC(=CC1)c1c[nH]c2ccc(Cl)cc12 |c:19| Show InChI InChI=1S/C23H25ClFN3O2S/c24-18-6-7-23-21(14-18)22(16-26-23)17-8-12-28(13-9-17)11-2-1-10-27-31(29,30)20-5-3-4-19(25)15-20/h3-8,14-16,26-27H,1-2,9-13H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Faculty of Pharmacy, Jagiellonian University Medical College , 9 Medyczna Street, 30-688 Kraków, Poland. Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6 receptor expressed in CHO-K1 cell membranes after 60 mins by scintillation counting				J Med Chem 60: 7483-7501 (2017) Article DOI: 10.1021/acs.jmedchem.7b00839 BindingDB Entry DOI: 10.7270/Q2K939ZD
					More data for this Ligand-Target Pair