BDBM50258640 2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-4-fluorophenyl)oxazole::CHEMBL466634

SMILES: Fc1ccc(-c2ncco2)c(c1)C1Cc2nccn2C1

InChI Key: InChIKey=NOCWBSIDJYRURZ-UHFFFAOYSA-N

Data: 1 KI  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50258640   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50258640 (2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-...) Show SMILES Fc1ccc(-c2ncco2)c(c1)C1Cc2nccn2C1 Show InChI InChI=1S/C15H12FN3O/c16-11-1-2-12(15-18-4-6-20-15)13(8-11)10-7-14-17-3-5-19(14)9-10/h1-6,8,10H,7,9H2	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	469	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of adrenergic alpha2A receptor (unknown origin)				Bioorg Med Chem Lett 19: 3113-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.166 BindingDB Entry DOI: 10.7270/Q2WS8T5T
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50258640 (2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-...) Show SMILES Fc1ccc(-c2ncco2)c(c1)C1Cc2nccn2C1 Show InChI InChI=1S/C15H12FN3O/c16-11-1-2-12(15-18-4-6-20-15)13(8-11)10-7-14-17-3-5-19(14)9-10/h1-6,8,10H,7,9H2	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	276	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1D receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.166 BindingDB Entry DOI: 10.7270/Q2WS8T5T
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50258640 (2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-...) Show SMILES Fc1ccc(-c2ncco2)c(c1)C1Cc2nccn2C1 Show InChI InChI=1S/C15H12FN3O/c16-11-1-2-12(15-18-4-6-20-15)13(8-11)10-7-14-17-3-5-19(14)9-10/h1-6,8,10H,7,9H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1A receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.166 BindingDB Entry DOI: 10.7270/Q2WS8T5T
					More data for this Ligand-Target Pair
Adrenergic alpha1B (Homo sapiens (Human))	BDBM50258640 (2-(2-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-yl)-...) Show SMILES Fc1ccc(-c2ncco2)c(c1)C1Cc2nccn2C1 Show InChI InChI=1S/C15H12FN3O/c16-11-1-2-12(15-18-4-6-20-15)13(8-11)10-7-14-17-3-5-19(14)9-10/h1-6,8,10H,7,9H2	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	990	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic alpha1B receptor expressed in CHO cells assessed as calcium mobilization by FLIPR				Bioorg Med Chem Lett 19: 3113-7 (2009) Article DOI: 10.1016/j.bmcl.2009.03.166 BindingDB Entry DOI: 10.7270/Q2WS8T5T
					More data for this Ligand-Target Pair