BDBM50258769 CHEMBL4096928

SMILES: Fc1ccc(c(F)c1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1

InChI Key: InChIKey=JXGHTJYIRPWBOB-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50258769   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (MOUSE)	BDBM50258769 (CHEMBL4096928) Show SMILES Fc1ccc(c(F)c1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C19H13ClF2N2O/c20-13-4-7-15(8-5-13)23-19(25)24-16-3-1-2-12(10-16)17-9-6-14(21)11-18(17)22/h1-11H,(H2,23,24,25)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	353	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor in CD-1 mouse cerebellar membranes assessed as inhibition of CP55,940-induced [35S]GTPgammaS binding after 60 m...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50258769 (CHEMBL4096928) Show SMILES Fc1ccc(c(F)c1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C19H13ClF2N2O/c20-13-4-7-15(8-5-13)23-19(25)24-16-3-1-2-12(10-16)17-9-6-14(21)11-18(17)22/h1-11H,(H2,23,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	353	n/a	n/a	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor (unknown origin) assessed as inhibition of CP55940-induced [35S]GTPgammaS binding				ACS Med Chem Lett 9: 1162-1163 (2018) Article DOI: 10.1021/acsmedchemlett.8b00575
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50258769 (CHEMBL4096928) Show SMILES Fc1ccc(c(F)c1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C19H13ClF2N2O/c20-13-4-7-15(8-5-13)23-19(25)24-16-3-1-2-12(10-16)17-9-6-14(21)11-18(17)22/h1-11H,(H2,23,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Usona Institute Curated by ChEMBL					Assay Description Allosteric modulation of CB1 receptor (unknown origin) assessed as inhibition of calcium mobilization by FLIPR assay				ACS Med Chem Lett 9: 1162-1163 (2018) Article DOI: 10.1021/acsmedchemlett.8b00575
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50258769 (CHEMBL4096928) Show SMILES Fc1ccc(c(F)c1)-c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C19H13ClF2N2O/c20-13-4-7-15(8-5-13)23-19(25)24-16-3-1-2-12(10-16)17-9-6-14(21)11-18(17)22/h1-11H,(H2,23,24,25)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute , Research Triangle Park, North Carolina 27709, United States. Curated by ChEMBL					Assay Description Allosteric modulation of human CB1 receptor expressed in CHO cells co-expressing Galpha16 assessed as inhibition of CP55,940-induced calcium mobiliza...				J Med Chem 60: 7410-7424 (2017) Article DOI: 10.1021/acs.jmedchem.7b00707 BindingDB Entry DOI: 10.7270/Q2XK8J0H
					More data for this Ligand-Target Pair