BDBM50258811 CHEMBL468097::N-cyclopropyl-3-(4-methoxyphenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-amine

SMILES: COc1ccc(cc1)-c1nnc2ccc(NC3CC3)nn12

InChI Key: InChIKey=INYTUQQBTZLTFF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50258811   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50258811 (CHEMBL468097 | N-cyclopropyl-3-(4-methoxyphenyl)-[...) Show SMILES COc1ccc(cc1)-c1nnc2ccc(NC3CC3)nn12 Show InChI InChI=1S/C15H15N5O/c1-21-12-6-2-10(3-7-12)15-18-17-14-9-8-13(19-20(14)15)16-11-4-5-11/h2-3,6-9,11H,4-5H2,1H3,(H,16,19)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of Pim1 (unknown origin) assessed as [32P] incorporation preincubated for 15 mins before ATP substrate addition by coupled spectrophotomet...				Bioorg Med Chem Lett 19: 3019-22 (2009) Article DOI: 10.1016/j.bmcl.2009.04.061 BindingDB Entry DOI: 10.7270/Q21J99PJ
					More data for this Ligand-Target Pair