BDBM50258820 5-(2-methoxyphenyl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile::CHEMBL512606
SMILES: COc1ccccc1-c1cncc(C#N)c1Nc1ccc2[nH]ccc2c1C
InChI Key: InChIKey=NJADSZALPMCYLV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50258820 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Protein kinase C delta type
(Homo sapiens (Human)) | BDBM50258820
(5-(2-methoxyphenyl)-4-(4-methyl-1H-indol-5-ylamino...)Show InChI InChI=1S/C22H18N4O/c1-14-16-9-10-25-20(16)8-7-19(14)26-22-15(11-23)12-24-13-18(22)17-5-3-4-6-21(17)27-2/h3-10,12-13,25H,1-2H3,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of human PKCdelta by IMAP assay |
Bioorg Med Chem Lett 19: 3623-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4 |
More data for this Ligand-Target Pair | |
Protein kinase C theta type
(Homo sapiens (Human)) | BDBM50258820
(5-(2-methoxyphenyl)-4-(4-methyl-1H-indol-5-ylamino...)Show InChI InChI=1S/C22H18N4O/c1-14-16-9-10-25-20(16)8-7-19(14)26-22-15(11-23)12-24-13-18(22)17-5-3-4-6-21(17)27-2/h3-10,12-13,25H,1-2H3,(H,24,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of human PKCtheta by IMAP assay |
Bioorg Med Chem Lett 19: 3623-6 (2009)
Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4 |
More data for this Ligand-Target Pair | |