BDBM50258823 4-(6-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)nicotinonitrile::CHEMBL467871

SMILES: CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2cc3cc[nH]c3cc2C)CC1

InChI Key: InChIKey=UOHOMVNTUXAPFC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258823   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50258823 (4-(6-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2cc3cc[nH]c3cc2C)CC1 Show InChI InChI=1S/C28H30N6O/c1-20-15-27-22(7-8-31-27)16-26(20)32-28-23(17-29)18-30-19-25(28)21-3-5-24(6-4-21)35-14-13-34-11-9-33(2)10-12-34/h3-8,15-16,18-19,31H,9-14H2,1-2H3,(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCdelta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50258823 (4-(6-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylp...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2cc3cc[nH]c3cc2C)CC1 Show InChI InChI=1S/C28H30N6O/c1-20-15-27-22(7-8-31-27)16-26(20)32-28-23(17-29)18-30-19-25(28)21-3-5-24(6-4-21)35-14-13-34-11-9-33(2)10-12-34/h3-8,15-16,18-19,31H,9-14H2,1-2H3,(H,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human PKCtheta by IMAP assay				Bioorg Med Chem Lett 19: 3623-6 (2009) Article DOI: 10.1016/j.bmcl.2009.04.126 BindingDB Entry DOI: 10.7270/Q29W0FD4
					More data for this Ligand-Target Pair