null

SMILES: OC1(CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1cncs1

InChI Key: InChIKey=KQUFTAYTBYGDSF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50259011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50259011 (8-(bis(2-chlorophenyl)methyl)-3-(thiazol-5-yl)-8-a...) Show SMILES OC1(CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1cncs1 |TLB:0:1:8:4.5| Show InChI InChI=1S/C23H22Cl2N2OS/c24-19-7-3-1-5-17(19)22(18-6-2-4-8-20(18)25)27-15-9-10-16(27)12-23(28,11-15)21-13-26-14-29-21/h1-8,13-16,22,28H,9-12H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2519-23 (2009) Article DOI: 10.1016/j.bmcl.2009.03.031 BindingDB Entry DOI: 10.7270/Q20V8CPS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50259011 (8-(bis(2-chlorophenyl)methyl)-3-(thiazol-5-yl)-8-a...) Show SMILES OC1(CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1cncs1 |TLB:0:1:8:4.5| Show InChI InChI=1S/C23H22Cl2N2OS/c24-19-7-3-1-5-17(19)22(18-6-2-4-8-20(18)25)27-15-9-10-16(27)12-23(28,11-15)21-13-26-14-29-21/h1-8,13-16,22,28H,9-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin from human cloned NOP receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2519-23 (2009) Article DOI: 10.1016/j.bmcl.2009.03.031 BindingDB Entry DOI: 10.7270/Q20V8CPS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50259011 (8-(bis(2-chlorophenyl)methyl)-3-(thiazol-5-yl)-8-a...) Show SMILES OC1(CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1cncs1 |TLB:0:1:8:4.5| Show InChI InChI=1S/C23H22Cl2N2OS/c24-19-7-3-1-5-17(19)22(18-6-2-4-8-20(18)25)27-15-9-10-16(27)12-23(28,11-15)21-13-26-14-29-21/h1-8,13-16,22,28H,9-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin from human cloned NOP receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2519-23 (2009) Article DOI: 10.1016/j.bmcl.2009.03.031 BindingDB Entry DOI: 10.7270/Q20V8CPS
					More data for this Ligand-Target Pair