null

SMILES: OC1(CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1cccnn1

InChI Key: InChIKey=IRRWZIHKAODIIS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50259012   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50259012 (8-(bis(2-chlorophenyl)methyl)-3-(pyridazin-3-yl)-8...) Show SMILES OC1(CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1cccnn1 |TLB:0:1:8:4.5| Show InChI InChI=1S/C24H23Cl2N3O/c25-20-8-3-1-6-18(20)23(19-7-2-4-9-21(19)26)29-16-11-12-17(29)15-24(30,14-16)22-10-5-13-27-28-22/h1-10,13,16-17,23,30H,11-12,14-15H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2519-23 (2009) Article DOI: 10.1016/j.bmcl.2009.03.031 BindingDB Entry DOI: 10.7270/Q20V8CPS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50259012 (8-(bis(2-chlorophenyl)methyl)-3-(pyridazin-3-yl)-8...) Show SMILES OC1(CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1cccnn1 |TLB:0:1:8:4.5| Show InChI InChI=1S/C24H23Cl2N3O/c25-20-8-3-1-6-18(20)23(19-7-2-4-9-21(19)26)29-16-11-12-17(29)15-24(30,14-16)22-10-5-13-27-28-22/h1-10,13,16-17,23,30H,11-12,14-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin from human cloned NOP receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2519-23 (2009) Article DOI: 10.1016/j.bmcl.2009.03.031 BindingDB Entry DOI: 10.7270/Q20V8CPS
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50259012 (8-(bis(2-chlorophenyl)methyl)-3-(pyridazin-3-yl)-8...) Show SMILES OC1(CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1cccnn1 |TLB:0:1:8:4.5| Show InChI InChI=1S/C24H23Cl2N3O/c25-20-8-3-1-6-18(20)23(19-7-2-4-9-21(19)26)29-16-11-12-17(29)15-24(30,14-16)22-10-5-13-27-28-22/h1-10,13,16-17,23,30H,11-12,14-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin from human cloned NOP receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2519-23 (2009) Article DOI: 10.1016/j.bmcl.2009.03.031 BindingDB Entry DOI: 10.7270/Q20V8CPS
					More data for this Ligand-Target Pair