BDBM50259047 5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4-methyl-N-(pyrrolidin-1-yl)-1H-pyrazole-3-carboxamide::CHEMBL510262

SMILES: Cc1c(nn(c1-c1ccc(Cl)s1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCC1

InChI Key: InChIKey=PCPLUKDORVRLOM-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259047   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50259047 (5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...) Show SMILES Cc1c(nn(c1-c1ccc(Cl)s1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCC1 Show InChI InChI=1S/C19H17Cl3N4OS/c1-11-17(19(27)24-25-8-2-3-9-25)23-26(14-5-4-12(20)10-13(14)21)18(11)15-6-7-16(22)28-15/h4-7,10H,2-3,8-9H2,1H3,(H,24,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB1 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50259047 (5-(5-chlorothiophen-2-yl)-1-(2,4-dichlorophenyl)-4...) Show SMILES Cc1c(nn(c1-c1ccc(Cl)s1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCC1 Show InChI InChI=1S/C19H17Cl3N4OS/c1-11-17(19(27)24-25-8-2-3-9-25)23-26(14-5-4-12(20)10-13(14)21)18(11)15-6-7-16(22)28-15/h4-7,10H,2-3,8-9H2,1H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.09E+4	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB2 receptor expressed in CHOK1 cells assessed as cAMP activity				Bioorg Med Chem Lett 19: 2546-50 (2009) Article DOI: 10.1016/j.bmcl.2009.03.046 BindingDB Entry DOI: 10.7270/Q2TB16SP
					More data for this Ligand-Target Pair