BDBM50259189 CHEMBL3084536::endo-8-(bis(2-chlorophenyl)methyl)-3-(5-cyanopyridin-2-yl)-8-azabicyclo[3.2.1]octane-3-carboxamide

SMILES: [H][C@]12CC[C@]([H])(C[C@](C1)(C(N)=O)c1ccc(cn1)C#N)N2C(c1ccccc1Cl)c1ccccc1Cl

InChI Key: InChIKey=AZUMDPMNGBWFOH-RTBURBONSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50259189 (CHEMBL3084536 | endo-8-(bis(2-chlorophenyl)methyl)...) Show SMILES [H][C@]12CC[C@]([H])(C[C@](C1)(C(N)=O)c1ccc(cn1)C#N)N2C(c1ccccc1Cl)c1ccccc1Cl |r,TLB:9:7:20:3.2| Show InChI InChI=1S/C27H24Cl2N4O/c28-22-7-3-1-5-20(22)25(21-6-2-4-8-23(21)29)33-18-10-11-19(33)14-27(13-18,26(31)34)24-12-9-17(15-30)16-32-24/h1-9,12,16,18-19,25H,10-11,13-14H2,(H2,31,34)/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin from human cloned ORL1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2482-6 (2009) Article DOI: 10.1016/j.bmcl.2009.03.057 BindingDB Entry DOI: 10.7270/Q2D21XH9
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50259189 (CHEMBL3084536 | endo-8-(bis(2-chlorophenyl)methyl)...) Show SMILES [H][C@]12CC[C@]([H])(C[C@](C1)(C(N)=O)c1ccc(cn1)C#N)N2C(c1ccccc1Cl)c1ccccc1Cl |r,TLB:9:7:20:3.2| Show InChI InChI=1S/C27H24Cl2N4O/c28-22-7-3-1-5-20(22)25(21-6-2-4-8-23(21)29)33-18-10-11-19(33)14-27(13-18,26(31)34)24-12-9-17(15-30)16-32-24/h1-9,12,16,18-19,25H,10-11,13-14H2,(H2,31,34)/t18-,19-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	481	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2482-6 (2009) Article DOI: 10.1016/j.bmcl.2009.03.057 BindingDB Entry DOI: 10.7270/Q2D21XH9
					More data for this Ligand-Target Pair