null

SMILES: Nc1ccc(NCCc2ccc(OCCCN3CCCCC3)cc2)nc1

InChI Key: InChIKey=SKLKYMNXKBBKKF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50259268   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50259268 (CHEMBL4084820) Show SMILES Nc1ccc(NCCc2ccc(OCCCN3CCCCC3)cc2)nc1 Show InChI InChI=1S/C21H30N4O/c22-19-7-10-21(24-17-19)23-12-11-18-5-8-20(9-6-18)26-16-4-15-25-13-2-1-3-14-25/h5-10,17H,1-4,11-16,22H2,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bioprojet-Biotech Curated by ChEMBL					Assay Description Antagonist activity at H3 receptor (unknown origin)				Eur J Med Chem 125: 565-572 (2017) Article DOI: 10.1016/j.ejmech.2016.09.074 BindingDB Entry DOI: 10.7270/Q20C4Z66
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50259268 (CHEMBL4084820) Show SMILES Nc1ccc(NCCc2ccc(OCCCN3CCCCC3)cc2)nc1 Show InChI InChI=1S/C21H30N4O/c22-19-7-10-21(24-17-19)23-12-11-18-5-8-20(9-6-18)26-16-4-15-25-13-2-1-3-14-25/h5-10,17H,1-4,11-16,22H2,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bioprojet-Biotech Curated by ChEMBL					Assay Description Antagonist activity at human H4 receptor expressed in CHO cells co-expressing Galphai2 assessed as inhibition of imetit-induced GTPgamma[35S] binding...				Eur J Med Chem 125: 565-572 (2017) Article DOI: 10.1016/j.ejmech.2016.09.074 BindingDB Entry DOI: 10.7270/Q20C4Z66
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50259268 (CHEMBL4084820) Show SMILES Nc1ccc(NCCc2ccc(OCCCN3CCCCC3)cc2)nc1 Show InChI InChI=1S/C21H30N4O/c22-19-7-10-21(24-17-19)23-12-11-18-5-8-20(9-6-18)26-16-4-15-25-13-2-1-3-14-25/h5-10,17H,1-4,11-16,22H2,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bioprojet-Biotech Curated by ChEMBL					Assay Description Antagonist activity at H4 receptor (unknown origin)				Eur J Med Chem 125: 565-572 (2017) Article DOI: 10.1016/j.ejmech.2016.09.074 BindingDB Entry DOI: 10.7270/Q20C4Z66
					More data for this Ligand-Target Pair