BDBM50259282 CHEMBL3084543::endo-8-(bis(2-chlorophenyl)methyl)-3-(3,5-difluoropyridin-2-yl)-8-azabicyclo[3.2.1]octane-3-carboxamide

SMILES: [H][C@]12CC[C@]([H])(C[C@](C1)(C(N)=O)c1ncc(F)cc1F)N2C(c1ccccc1Cl)c1ccccc1Cl

InChI Key: InChIKey=APSCTLSVGWMNTN-IAGOWNOFSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50259282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50259282 (CHEMBL3084543 | endo-8-(bis(2-chlorophenyl)methyl)...) Show SMILES [H][C@]12CC[C@]([H])(C[C@](C1)(C(N)=O)c1ncc(F)cc1F)N2C(c1ccccc1Cl)c1ccccc1Cl |r,TLB:9:7:20:3.2| Show InChI InChI=1S/C26H23Cl2F2N3O/c27-20-7-3-1-5-18(20)23(19-6-2-4-8-21(19)28)33-16-9-10-17(33)13-26(12-16,25(31)34)24-22(30)11-15(29)14-32-24/h1-8,11,14,16-17,23H,9-10,12-13H2,(H2,31,34)/t16-,17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin from human cloned ORL1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2482-6 (2009) Article DOI: 10.1016/j.bmcl.2009.03.057 BindingDB Entry DOI: 10.7270/Q2D21XH9
					More data for this Ligand-Target Pair