BindingDB logo
myBDB logout

null

SMILES: [H][C@]12CC[C@]([H])(C[C@](C1)(C(N)=O)c1cc(C(O)=O)c(F)cn1)N2C(c1ccccc1Cl)c1ccccc1Cl

InChI Key: InChIKey=BZDGXSLJPOLSJO-HZPDHXFCSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50259347   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nociceptin receptor


(Homo sapiens (Human))		BDBM50259347
PNG
(CHEMBL3084546 | endo-2-(8-(bis(2-chlorophenyl)meth...)
Show SMILES [H][C@]12CC[C@]([H])(C[C@](C1)(C(N)=O)c1cc(C(O)=O)c(F)cn1)N2C(c1ccccc1Cl)c1ccccc1Cl |r,TLB:9:7:22:3.2|
Show InChI InChI=1S/C27H24Cl2FN3O3/c28-20-7-3-1-5-17(20)24(18-6-2-4-8-21(18)29)33-15-9-10-16(33)13-27(12-15,26(31)36)23-11-19(25(34)35)22(30)14-32-23/h1-8,11,14-16,24H,9-10,12-13H2,(H2,31,36)(H,34,35)/t15-,16-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Displacement of [125I][Tyr14]nociceptin from human cloned ORL1 receptor expressed in CHO cells

Bioorg Med Chem Lett 19: 2482-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.057
BindingDB Entry DOI: 10.7270/Q2D21XH9
More data for this
Ligand-Target Pair