BDBM50259478 3-(Pyridin-4-ylamino)-4-{[1-(1,3-thiazol-2-yl)ethyl]-amino}cyclobut-3-ene-1,2-dione::CHEMBL467729

SMILES: CC(Nc1c(Nc2ccncc2)c(=O)c1=O)c1nccs1

InChI Key: InChIKey=VEEIJXOIIPWFLM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50259478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50259478 (3-(Pyridin-4-ylamino)-4-{[1-(1,3-thiazol-2-yl)ethy...) Show SMILES CC(Nc1c(Nc2ccncc2)c(=O)c1=O)c1nccs1 Show InChI InChI=1S/C14H12N4O2S/c1-8(14-16-6-7-21-14)17-10-11(13(20)12(10)19)18-9-2-4-15-5-3-9/h2-8,17H,1H3,(H,15,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human recombinant MK2				Bioorg Med Chem 17: 3342-51 (2009) Article DOI: 10.1016/j.bmc.2009.03.041 BindingDB Entry DOI: 10.7270/Q2WW7HK4
					More data for this Ligand-Target Pair