BDBM50259551 CHEMBL3084557::endo-8-(bis(2-chlorophenyl)methyl)-3-(4-chlorobenzyl)-8-azabicyclo[3.2.1]octan-3-amine

SMILES: [H][C@]12CC[C@]([H])(C[C@](N)(Cc3ccc(Cl)cc3)C1)N2C(c1ccccc1Cl)c1ccccc1Cl

InChI Key: InChIKey=GMLXFHAZVSYSMP-NHCUHLMSSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50259551   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50259551 (CHEMBL3084557 | endo-8-(bis(2-chlorophenyl)methyl)...) Show SMILES [H][C@]12CC[C@]([H])(C[C@](N)(Cc3ccc(Cl)cc3)C1)N2C(c1ccccc1Cl)c1ccccc1Cl |r,TLB:8:7:18:3.2| Show InChI InChI=1S/C27H27Cl3N2/c28-19-11-9-18(10-12-19)15-27(31)16-20-13-14-21(17-27)32(20)26(22-5-1-3-7-24(22)29)23-6-2-4-8-25(23)30/h1-12,20-21,26H,13-17,31H2/t20-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]nociceptin from human cloned ORL1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2482-6 (2009) Article DOI: 10.1016/j.bmcl.2009.03.057 BindingDB Entry DOI: 10.7270/Q2D21XH9
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50259551 (CHEMBL3084557 | endo-8-(bis(2-chlorophenyl)methyl)...) Show SMILES [H][C@]12CC[C@]([H])(C[C@](N)(Cc3ccc(Cl)cc3)C1)N2C(c1ccccc1Cl)c1ccccc1Cl |r,TLB:8:7:18:3.2| Show InChI InChI=1S/C27H27Cl3N2/c28-19-11-9-18(10-12-19)15-27(31)16-20-13-14-21(17-27)32(20)26(22-5-1-3-7-24(22)29)23-6-2-4-8-25(23)30/h1-12,20-21,26H,13-17,31H2/t20-,21-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	447	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2482-6 (2009) Article DOI: 10.1016/j.bmcl.2009.03.057 BindingDB Entry DOI: 10.7270/Q2D21XH9
					More data for this Ligand-Target Pair