BDBM50259600 3-{[(1R)-1-Phenylethyl]amino}-4-[(2-phenylpyridin-4-yl)amino]cyclobut-3-ene-1,2-dione::CHEMBL511419

SMILES: C[C@@H](Nc1c(Nc2ccnc(c2)-c2ccccc2)c(=O)c1=O)c1ccccc1

InChI Key: InChIKey=KDSILWKEQMVTNF-OAHLLOKOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50259600   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50259600 (3-{[(1R)-1-Phenylethyl]amino}-4-[(2-phenylpyridin-...) Show SMILES C[C@@H](Nc1c(Nc2ccnc(c2)-c2ccccc2)c(=O)c1=O)c1ccccc1 |r| Show InChI InChI=1S/C23H19N3O2/c1-15(16-8-4-2-5-9-16)25-20-21(23(28)22(20)27)26-18-12-13-24-19(14-18)17-10-6-3-7-11-17/h2-15,25H,1H3,(H,24,26)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human recombinant MK2				Bioorg Med Chem 17: 3342-51 (2009) Article DOI: 10.1016/j.bmc.2009.03.041 BindingDB Entry DOI: 10.7270/Q2WW7HK4
					More data for this Ligand-Target Pair