BDBM50260204 CHEMBL4100110

SMILES: CNc1ncc2CN(C(=O)N([C@H]3CCCN(C3)C(=O)\C=C\CN(C)C)c2n1)c1c(Cl)c(OC)cc(OC)c1Cl

InChI Key: InChIKey=DPADFABSXXWTCR-LKUPDRCFSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50260204   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50260204 (CHEMBL4100110) Show SMILES CNc1ncc2CN(C(=O)N([C@H]3CCCN(C3)C(=O)\C=C\CN(C)C)c2n1)c1c(Cl)c(OC)cc(OC)c1Cl |r| Show InChI InChI=1S/C26H33Cl2N7O4/c1-29-25-30-13-16-14-34(23-21(27)18(38-4)12-19(39-5)22(23)28)26(37)35(24(16)31-25)17-8-6-11-33(15-17)20(36)9-7-10-32(2)3/h7,9,12-13,17H,6,8,10-11,14-15H2,1-5H3,(H,29,30,31)/b9-7+/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged FGFR1 cytoplasmic domain (308 to 731 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by ...				Eur J Med Chem 135: 531-543 (2017) Article DOI: 10.1016/j.ejmech.2017.04.049 BindingDB Entry DOI: 10.7270/Q2K076QF
					More data for this Ligand-Target Pair