BDBM50260207 CHEMBL4102560

SMILES: CNc1ncc2CN(C(=O)N(CCCNC(=O)\C=C\CN(C)C)c2n1)c1c(Cl)c(OC)cc(OC)c1Cl

InChI Key: InChIKey=ODGUJMYPUJPRKK-SOFGYWHQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50260207   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50260207 (CHEMBL4102560) Show SMILES CNc1ncc2CN(C(=O)N(CCCNC(=O)\C=C\CN(C)C)c2n1)c1c(Cl)c(OC)cc(OC)c1Cl Show InChI InChI=1S/C24H31Cl2N7O4/c1-27-23-29-13-15-14-33(21-19(25)16(36-4)12-17(37-5)20(21)26)24(35)32(22(15)30-23)11-7-9-28-18(34)8-6-10-31(2)3/h6,8,12-13H,7,9-11,14H2,1-5H3,(H,28,34)(H,27,29,30)/b8-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged FGFR1 cytoplasmic domain (308 to 731 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by ...				Eur J Med Chem 135: 531-543 (2017) Article DOI: 10.1016/j.ejmech.2017.04.049 BindingDB Entry DOI: 10.7270/Q2K076QF
					More data for this Ligand-Target Pair