BDBM50260608 CHEMBL4098594

SMILES: Cc1nc2C(O)CCCn2c(=O)c1CCN1CCN(CC1)c1noc2cc(F)ccc12

InChI Key: InChIKey=NAYOORQZOBSVOI-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50260608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50260608 (CHEMBL4098594) Show SMILES Cc1nc2C(O)CCCn2c(=O)c1CCN1CCN(CC1)c1noc2cc(F)ccc12 Show InChI InChI=1S/C22H26FN5O3/c1-14-16(22(30)28-7-2-3-18(29)21(28)24-14)6-8-26-9-11-27(12-10-26)20-17-5-4-15(23)13-19(17)31-25-20/h4-5,13,18,29H,2-3,6-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Xinjiang Technical Institute of Physics and Chemistry Curated by ChEMBL					Assay Description Antagonist activity at 5-HT2A receptor (unknown origin) after 10 mins by calcium 5 dye based FLIPR assay				Bioorg Med Chem 25: 4904-4916 (2017) Article DOI: 10.1016/j.bmc.2017.07.040 BindingDB Entry DOI: 10.7270/Q2Z3222T
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50260608 (CHEMBL4098594) Show SMILES Cc1nc2C(O)CCCn2c(=O)c1CCN1CCN(CC1)c1noc2cc(F)ccc12 Show InChI InChI=1S/C22H26FN5O3/c1-14-16(22(30)28-7-2-3-18(29)21(28)24-14)6-8-26-9-11-27(12-10-26)20-17-5-4-15(23)13-19(17)31-25-20/h4-5,13,18,29H,2-3,6-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
Xinjiang Technical Institute of Physics and Chemistry Curated by ChEMBL					Assay Description Antagonist activity at dopamine D2 receptor (unknown origin) after 60 mins by Ultra lance cAMP assay				Bioorg Med Chem 25: 4904-4916 (2017) Article DOI: 10.1016/j.bmc.2017.07.040 BindingDB Entry DOI: 10.7270/Q2Z3222T
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50260608 (CHEMBL4098594) Show SMILES Cc1nc2C(O)CCCn2c(=O)c1CCN1CCN(CC1)c1noc2cc(F)ccc12 Show InChI InChI=1S/C22H26FN5O3/c1-14-16(22(30)28-7-2-3-18(29)21(28)24-14)6-8-26-9-11-27(12-10-26)20-17-5-4-15(23)13-19(17)31-25-20/h4-5,13,18,29H,2-3,6-12H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Xinjiang Technical Institute of Physics and Chemistry Curated by ChEMBL					Assay Description Agonist activity at 5-HT1A receptor (unknown origin) after 60 mins by Ultra lance cAMP assay				Bioorg Med Chem 25: 4904-4916 (2017) Article DOI: 10.1016/j.bmc.2017.07.040 BindingDB Entry DOI: 10.7270/Q2Z3222T
					More data for this Ligand-Target Pair