BDBM50260630 2-(4-(6-chloro-2-(pentan-3-ylthio)-3H-benzo[d]imidazol-5-yl)-2-methylpiperazin-1-yl)ethanol::CHEMBL494219

SMILES: CCC(CC)Sc1nc2cc(Cl)c(cc2[nH]1)N1CCN(CCO)C(C)C1

InChI Key: InChIKey=PHNRBVJUYTWJPU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260630   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50260630 (2-(4-(6-chloro-2-(pentan-3-ylthio)-3H-benzo[d]imid...) Show SMILES CCC(CC)Sc1nc2cc(Cl)c(cc2[nH]1)N1CCN(CCO)C(C)C1 Show InChI InChI=1S/C19H29ClN4OS/c1-4-14(5-2)26-19-21-16-10-15(20)18(11-17(16)22-19)24-7-6-23(8-9-25)13(3)12-24/h10-11,13-14,25H,4-9,12H2,1-3H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr14-NC/OFQ from human ORL1 receptor				Bioorg Med Chem Lett 18: 3282-5 (2008) Article DOI: 10.1016/j.bmcl.2008.04.037 BindingDB Entry DOI: 10.7270/Q2542NDJ
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50260630 (2-(4-(6-chloro-2-(pentan-3-ylthio)-3H-benzo[d]imid...) Show SMILES CCC(CC)Sc1nc2cc(Cl)c(cc2[nH]1)N1CCN(CCO)C(C)C1 Show InChI InChI=1S/C19H29ClN4OS/c1-4-14(5-2)26-19-21-16-10-15(20)18(11-17(16)22-19)24-7-6-23(8-9-25)13(3)12-24/h10-11,13-14,25H,4-9,12H2,1-3H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 18: 3282-5 (2008) Article DOI: 10.1016/j.bmcl.2008.04.037 BindingDB Entry DOI: 10.7270/Q2542NDJ
					More data for this Ligand-Target Pair