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BDBM50260720 1-(5,6-bis(4-ethoxyphenyl)pyrazin-2-yl)-4-(ethylamino)piperidine-4-carboxamide::CHEMBL495892

SMILES: CCNC1(CCN(CC1)c1cnc(-c2ccc(OCC)cc2)c(n1)-c1ccc(OCC)cc1)C(N)=O

InChI Key: InChIKey=MXYAUZSZXRTBLD-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50260720   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))		BDBM50260720
PNG
(1-(5,6-bis(4-ethoxyphenyl)pyrazin-2-yl)-4-(ethylam...)
Show SMILES CCNC1(CCN(CC1)c1cnc(-c2ccc(OCC)cc2)c(n1)-c1ccc(OCC)cc1)C(N)=O
Show InChI InChI=1S/C28H35N5O3/c1-4-31-28(27(29)34)15-17-33(18-16-28)24-19-30-25(20-7-11-22(12-8-20)35-5-2)26(32-24)21-9-13-23(14-10-21)36-6-3/h7-14,19,31H,4-6,15-18H2,1-3H3,(H2,29,34)
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Similars
Article
PubMed
 2.84n/an/an/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at human CB1 receptor expressed in SF9 cells assessed as inhibition of CP-55940-stimulated GTPgammaS binding

Bioorg Med Chem Lett 18: 3376-81 (2008)


Article DOI: 10.1016/j.bmcl.2008.04.022
BindingDB Entry DOI: 10.7270/Q2QR4Z0T
More data for this
Ligand-Target Pair