Found 8 hits for monomerid = 50260722 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
D-amino-acid oxidase
(Homo sapiens (Human)) | BDBM50260722
(4-(4-chlorophenethyl)-1H-pyrrole-2-carboxylic acid...)Show InChI InChI=1S/C13H12ClNO2/c14-11-5-3-9(4-6-11)1-2-10-7-12(13(16)17)15-8-10/h3-8,15H,1-2H2,(H,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
| PDB Article PubMed
| 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serine |
J Med Chem 56: 3710-24 (2013)
Article DOI: 10.1021/jm4002583 BindingDB Entry DOI: 10.7270/Q2X92CPC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
D-amino-acid oxidase
(Homo sapiens (Human)) | BDBM50260722
(4-(4-chlorophenethyl)-1H-pyrrole-2-carboxylic acid...)Show InChI InChI=1S/C13H12ClNO2/c14-11-5-3-9(4-6-11)1-2-10-7-12(13(16)17)15-8-10/h3-8,15H,1-2H2,(H,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
| PDB Article PubMed
| n/a | n/a | 238 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme
Curated by ChEMBL
| Assay Description Inhibition of human DAO |
Bioorg Med Chem Lett 18: 3386-91 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.020 BindingDB Entry DOI: 10.7270/Q2WQ03KS |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
D-amino-acid oxidase
(Homo sapiens (Human)) | BDBM50260722
(4-(4-chlorophenethyl)-1H-pyrrole-2-carboxylic acid...)Show InChI InChI=1S/C13H12ClNO2/c14-11-5-3-9(4-6-11)1-2-10-7-12(13(16)17)15-8-10/h3-8,15H,1-2H2,(H,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
| PDB Article PubMed
| n/a | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant DAAO by stopped flow spectrophotometric analysis in presence of FAD |
J Med Chem 56: 3710-24 (2013)
Article DOI: 10.1021/jm4002583 BindingDB Entry DOI: 10.7270/Q2X92CPC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
D-amino-acid oxidase
(Homo sapiens (Human)) | BDBM50260722
(4-(4-chlorophenethyl)-1H-pyrrole-2-carboxylic acid...)Show InChI InChI=1S/C13H12ClNO2/c14-11-5-3-9(4-6-11)1-2-10-7-12(13(16)17)15-8-10/h3-8,15H,1-2H2,(H,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
| PDB Article PubMed
| n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant DAAO at 520 nm spectral modification by spectrophotometric analysis in presence of FAD |
J Med Chem 56: 3710-24 (2013)
Article DOI: 10.1021/jm4002583 BindingDB Entry DOI: 10.7270/Q2X92CPC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
D-amino-acid oxidase
(Homo sapiens (Human)) | BDBM50260722
(4-(4-chlorophenethyl)-1H-pyrrole-2-carboxylic acid...)Show InChI InChI=1S/C13H12ClNO2/c14-11-5-3-9(4-6-11)1-2-10-7-12(13(16)17)15-8-10/h3-8,15H,1-2H2,(H,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
| PDB Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant DAAO after 1 hr by coupled enzyme assay in presence of D-serine |
J Med Chem 56: 3710-24 (2013)
Article DOI: 10.1021/jm4002583 BindingDB Entry DOI: 10.7270/Q2X92CPC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
D-amino-acid oxidase
(Homo sapiens (Human)) | BDBM50260722
(4-(4-chlorophenethyl)-1H-pyrrole-2-carboxylic acid...)Show InChI InChI=1S/C13H12ClNO2/c14-11-5-3-9(4-6-11)1-2-10-7-12(13(16)17)15-8-10/h3-8,15H,1-2H2,(H,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
| PDB Article PubMed
| n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant DAAO at 490 nm spectral modification by spectrophotometric analysis in presence of FAD |
J Med Chem 56: 3710-24 (2013)
Article DOI: 10.1021/jm4002583 BindingDB Entry DOI: 10.7270/Q2X92CPC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
D-Aspartate Oxidase (DDO)
(Homo sapiens (Human)) | BDBM50260722
(4-(4-chlorophenethyl)-1H-pyrrole-2-carboxylic acid...)Show InChI InChI=1S/C13H12ClNO2/c14-11-5-3-9(4-6-11)1-2-10-7-12(13(16)17)15-8-10/h3-8,15H,1-2H2,(H,16,17) | PDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme
Curated by ChEMBL
| Assay Description Inhibition of human DDO |
Bioorg Med Chem Lett 18: 3386-91 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.020 BindingDB Entry DOI: 10.7270/Q2WQ03KS |
More data for this Ligand-Target Pair | |
D-amino-acid oxidase
(Homo sapiens (Human)) | BDBM50260722
(4-(4-chlorophenethyl)-1H-pyrrole-2-carboxylic acid...)Show InChI InChI=1S/C13H12ClNO2/c14-11-5-3-9(4-6-11)1-2-10-7-12(13(16)17)15-8-10/h3-8,15H,1-2H2,(H,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
| PDB Article PubMed
| n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant DAAO at 520 nm spectral modification by stopped flow spectrophotometric analysis in presence of FAD |
J Med Chem 56: 3710-24 (2013)
Article DOI: 10.1021/jm4002583 BindingDB Entry DOI: 10.7270/Q2X92CPC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |