BDBM50261130 CHEMBL498774::N-Ethyl-2-piperidin-1-yl-N-{2-[2-(trifluoromethoxy)phenyl]-ethyl}ethanamine

SMILES: CCN(CCN1CCCCC1)CCc1ccccc1OC(F)(F)F

InChI Key: InChIKey=GYJUQRIRWMPONQ-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50261130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50261130 (CHEMBL498774 | N-Ethyl-2-piperidin-1-yl-N-{2-[2-(t...) Show SMILES CCN(CCN1CCCCC1)CCc1ccccc1OC(F)(F)F Show InChI InChI=1S/C18H27F3N2O/c1-2-22(14-15-23-11-6-3-7-12-23)13-10-16-8-4-5-9-17(16)24-18(19,20)21/h4-5,8-9H,2-3,6-7,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H](+)pentazocine from opioid sigma1 receptor in rat brain homogenate				J Med Chem 51: 3322-5 (2008) Article DOI: 10.1021/jm7013666 BindingDB Entry DOI: 10.7270/Q24749N1
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50261130 (CHEMBL498774 | N-Ethyl-2-piperidin-1-yl-N-{2-[2-(t...) Show SMILES CCN(CCN1CCCCC1)CCc1ccccc1OC(F)(F)F Show InChI InChI=1S/C18H27F3N2O/c1-2-22(14-15-23-11-6-3-7-12-23)13-10-16-8-4-5-9-17(16)24-18(19,20)21/h4-5,8-9H,2-3,6-7,10-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	213	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity at dopamine D2 receptor (unknown origin)				J Med Chem 51: 3322-5 (2008) Article DOI: 10.1021/jm7013666 BindingDB Entry DOI: 10.7270/Q24749N1
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50261130 (CHEMBL498774 | N-Ethyl-2-piperidin-1-yl-N-{2-[2-(t...) Show SMILES CCN(CCN1CCCCC1)CCc1ccccc1OC(F)(F)F Show InChI InChI=1S/C18H27F3N2O/c1-2-22(14-15-23-11-6-3-7-12-23)13-10-16-8-4-5-9-17(16)24-18(19,20)21/h4-5,8-9H,2-3,6-7,10-15H2,1H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.53E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity at DAT (unknown origin)				J Med Chem 51: 3322-5 (2008) Article DOI: 10.1021/jm7013666 BindingDB Entry DOI: 10.7270/Q24749N1
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50261130 (CHEMBL498774 | N-Ethyl-2-piperidin-1-yl-N-{2-[2-(t...) Show SMILES CCN(CCN1CCCCC1)CCc1ccccc1OC(F)(F)F Show InChI InChI=1S/C18H27F3N2O/c1-2-22(14-15-23-11-6-3-7-12-23)13-10-16-8-4-5-9-17(16)24-18(19,20)21/h4-5,8-9H,2-3,6-7,10-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.81E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity at NET (unknown origin)				J Med Chem 51: 3322-5 (2008) Article DOI: 10.1021/jm7013666 BindingDB Entry DOI: 10.7270/Q24749N1
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50261130 (CHEMBL498774 | N-Ethyl-2-piperidin-1-yl-N-{2-[2-(t...) Show SMILES CCN(CCN1CCCCC1)CCc1ccccc1OC(F)(F)F Show InChI InChI=1S/C18H27F3N2O/c1-2-22(14-15-23-11-6-3-7-12-23)13-10-16-8-4-5-9-17(16)24-18(19,20)21/h4-5,8-9H,2-3,6-7,10-15H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity at SERT (unknown origin)				J Med Chem 51: 3322-5 (2008) Article DOI: 10.1021/jm7013666 BindingDB Entry DOI: 10.7270/Q24749N1
					More data for this Ligand-Target Pair