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SMILES: Cc1c(C2=CC=C(Cl)C2=C)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1F

InChI Key: InChIKey=MQBKLGXUDJZCII-QHCPKHFHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261240   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Homo sapiens (Human))		BDBM50261240
PNG
((R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethy...)
Show SMILES Cc1c(C2=CC=C(Cl)C2=C)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1F |r,t:3,5|
Show InChI InChI=1S/C26H22ClF2N3O2/c1-15-18(11-12-20(15)27)24-16(2)31(13-19-21(28)9-6-10-22(19)29)26(34)32(25(24)33)14-23(30)17-7-4-3-5-8-17/h3-12,23H,1,13-14,30H2,2H3/t23-/m0/s1
PDB

KEGG

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PC cid
PC sid
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Article
PubMed
 14n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc

Curated by ChEMBL


Assay Description
Binding affinity at human GnRH receptor

J Med Chem 51: 3331-48 (2008)


Article DOI: 10.1021/jm701249f
BindingDB Entry DOI: 10.7270/Q2KD1XQ0
More data for this
Ligand-Target Pair