null

SMILES: N[C@@H](Cn1c(=O)c(c2SC[C@H](c3ccccc3)n2c1=O)-c1ccccc1F)c1ccccc1

InChI Key: InChIKey=IVIDZBGALXXDPN-FCHUYYIVSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261246   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50261246 ((S)-6-((R)-2-amino-2-phenylethyl)-8-(2-fluoropheny...) Show SMILES N[C@@H](Cn1c(=O)c(c2SC[C@H](c3ccccc3)n2c1=O)-c1ccccc1F)c1ccccc1 |r,wD:1.0,10.10,(-6.59,-28.2,;-6.6,-26.66,;-5.26,-25.89,;-3.93,-26.65,;-2.6,-25.88,;-2.6,-24.34,;-1.27,-26.65,;-1.27,-28.19,;-.13,-29.21,;-.75,-30.61,;-2.27,-30.45,;-3.29,-31.59,;-4.8,-31.27,;-5.83,-32.42,;-5.35,-33.89,;-3.83,-34.2,;-2.81,-33.05,;-2.59,-28.96,;-3.93,-28.19,;-5.26,-28.97,;.06,-25.88,;1.39,-26.65,;2.73,-25.88,;2.72,-24.34,;1.38,-23.57,;.05,-24.35,;-1.29,-23.59,;-7.93,-25.9,;-7.93,-24.36,;-9.26,-23.59,;-10.6,-24.36,;-10.59,-25.91,;-9.25,-26.67,)| Show InChI InChI=1S/C26H22FN3O2S/c27-20-14-8-7-13-19(20)23-24(31)29(15-21(28)17-9-3-1-4-10-17)26(32)30-22(16-33-25(23)30)18-11-5-2-6-12-18/h1-14,21-22H,15-16,28H2/t21-,22+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc Curated by ChEMBL					Assay Description Binding affinity at human GnRH receptor				J Med Chem 51: 3331-48 (2008) Article DOI: 10.1021/jm701249f BindingDB Entry DOI: 10.7270/Q2KD1XQ0
					More data for this Ligand-Target Pair