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SMILES: COc1cccc(c1F)-c1nn(Cc2c(F)cccc2C(F)(F)F)c(=O)n(C[C@H](N)c2ccccc2)c1=O

InChI Key: InChIKey=MSAMWXAZPNGSOJ-FQEVSTJZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261248   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Homo sapiens (Human))		BDBM50261248
PNG
((R)-2-(2-fluoro-6-(trifluoromethyl)benzyl)-4-(2-am...)
Show SMILES COc1cccc(c1F)-c1nn(Cc2c(F)cccc2C(F)(F)F)c(=O)n(C[C@H](N)c2ccccc2)c1=O |r|
Show InChI InChI=1S/C26H21F5N4O3/c1-38-21-12-5-9-16(22(21)28)23-24(36)34(14-20(32)15-7-3-2-4-8-15)25(37)35(33-23)13-17-18(26(29,30)31)10-6-11-19(17)27/h2-12,20H,13-14,32H2,1H3/t20-/m0/s1
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Similars
Article
PubMed
 13n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc

Curated by ChEMBL


Assay Description
Binding affinity at human GnRH receptor

J Med Chem 51: 3331-48 (2008)


Article DOI: 10.1021/jm701249f
BindingDB Entry DOI: 10.7270/Q2KD1XQ0
More data for this
Ligand-Target Pair