BDBM50261702 2-Methyl-c-5-[4-{2-(5-methyl-2-phenyloxazol-4-yl)ethoxy}benzyl]-1,3-dioxane-s-2-carboxylic acid::CHEMBL467349
SMILES: Cc1oc(nc1CCOc1ccc(C[C@H]2CO[C@](C)(OC2)C(O)=O)cc1)-c1ccccc1
InChI Key: InChIKey=QJSMCQQAUANXCW-KJDSRRNHSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor (Homo sapiens (Human)) | BDBM50261702 (2-Methyl-c-5-[4-{2-(5-methyl-2-phenyloxazol-4-yl)e...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a |
Zydus Research Centre Curated by ChEMBL | Assay Description Agonist activity at PPARgamma (unknown origin) expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assa... | Bioorg Med Chem 16: 7117-27 (2008) Article DOI: 10.1016/j.bmc.2008.06.050 BindingDB Entry DOI: 10.7270/Q2K93792 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human)) | BDBM50261702 (2-Methyl-c-5-[4-{2-(5-methyl-2-phenyloxazol-4-yl)e...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.272 | n/a | n/a | n/a | n/a |
Zydus Research Centre Curated by ChEMBL | Assay Description Agonist activity at PPARalpha (unknown origin) expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assa... | Bioorg Med Chem 16: 7117-27 (2008) Article DOI: 10.1016/j.bmc.2008.06.050 BindingDB Entry DOI: 10.7270/Q2K93792 | |||||||||||
More data for this Ligand-Target Pair |