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BDBM50261766 (+/-)-exo-(1R,2R,4R)-2-(6-chloropyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::CHEMBL513692

SMILES: Clc1ccc(cn1)[C@H]1C[C@H]2CC[C@H]1N2

InChI Key: InChIKey=NLPRAJRHRHZCQQ-OPRDCNLKSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50261766   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-4


(Homo sapiens (Human))
BDBM50261766
PNG
((+/-)-exo-(1R,2R,4R)-2-(6-chloropyridin-3-yl)-7-az...)
Show SMILES Clc1ccc(cn1)[C@H]1C[C@H]2CC[C@H]1N2 |r,THB:4:7:10.11:13|
Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2/t8-,9-,10-/m1/s1
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KEGG

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
7.60n/an/an/an/an/an/an/an/a



Università degli Studi di Milano

Curated by ChEMBL


Assay Description
Binding affinity to alpha4beta2 nAChR (unknown origin)


Bioorg Med Chem Lett 18: 4651-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.016
BindingDB Entry DOI: 10.7270/Q20C4VKW
More data for this
Ligand-Target Pair