BDBM50261879 2-Methyl-c-5-{4-[2-(5-methyl-2-(5-methylthiophen-2-yl)oxazol-4-yl)ethoxy]benzyl}-1,3-dioxane-s-2-carboxylic acid::CHEMBL468160

SMILES: Cc1ccc(s1)-c1nc(CCOc2ccc(C[C@H]3CO[C@](C)(OC3)C(O)=O)cc2)c(C)o1

InChI Key: InChIKey=KJZIXZXYBFJCIE-OWWJJEGGSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50261879   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50261879 (2-Methyl-c-5-{4-[2-(5-methyl-2-(5-methylthiophen-2...) Show SMILES Cc1ccc(s1)-c1nc(CCOc2ccc(C[C@H]3CO[C@](C)(OC3)C(O)=O)cc2)c(C)o1 |r,wU:20.25,17.17,wD:20.21,(-9.95,-10.46,;-8.61,-11.22,;-7.21,-10.58,;-6.17,-11.72,;-6.93,-13.06,;-8.44,-12.75,;-6.29,-14.46,;-4.79,-14.77,;-4.61,-16.3,;-3.27,-17.06,;-1.94,-16.28,;-.6,-17.04,;.73,-16.26,;2.07,-17.02,;3.39,-16.24,;3.38,-14.7,;4.71,-13.92,;6.05,-14.68,;7.37,-13.89,;8.71,-14.65,;8.72,-16.19,;10.18,-15.74,;7.39,-16.97,;6.05,-16.21,;9.2,-17.65,;10.71,-17.96,;8.18,-18.8,;2.03,-13.94,;.71,-14.73,;-6.01,-16.93,;-6.32,-18.44,;-7.05,-15.8,)| Show InChI InChI=1S/C24H27NO6S/c1-15-4-9-21(32-15)22-25-20(16(2)31-22)10-11-28-19-7-5-17(6-8-19)12-18-13-29-24(3,23(26)27)30-14-18/h4-9,18H,10-14H2,1-3H3,(H,26,27)/t18-,24+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	239	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Agonist activity at PPARgamma (unknown origin) expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assa...				Bioorg Med Chem 16: 7117-27 (2008) Article DOI: 10.1016/j.bmc.2008.06.050 BindingDB Entry DOI: 10.7270/Q2K93792
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50261879 (2-Methyl-c-5-{4-[2-(5-methyl-2-(5-methylthiophen-2...) Show SMILES Cc1ccc(s1)-c1nc(CCOc2ccc(C[C@H]3CO[C@](C)(OC3)C(O)=O)cc2)c(C)o1 |r,wU:20.25,17.17,wD:20.21,(-9.95,-10.46,;-8.61,-11.22,;-7.21,-10.58,;-6.17,-11.72,;-6.93,-13.06,;-8.44,-12.75,;-6.29,-14.46,;-4.79,-14.77,;-4.61,-16.3,;-3.27,-17.06,;-1.94,-16.28,;-.6,-17.04,;.73,-16.26,;2.07,-17.02,;3.39,-16.24,;3.38,-14.7,;4.71,-13.92,;6.05,-14.68,;7.37,-13.89,;8.71,-14.65,;8.72,-16.19,;10.18,-15.74,;7.39,-16.97,;6.05,-16.21,;9.2,-17.65,;10.71,-17.96,;8.18,-18.8,;2.03,-13.94,;.71,-14.73,;-6.01,-16.93,;-6.32,-18.44,;-7.05,-15.8,)| Show InChI InChI=1S/C24H27NO6S/c1-15-4-9-21(32-15)22-25-20(16(2)31-22)10-11-28-19-7-5-17(6-8-19)12-18-13-29-24(3,23(26)27)30-14-18/h4-9,18H,10-14H2,1-3H3,(H,26,27)/t18-,24+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a
Zydus Research Centre Curated by ChEMBL					Assay Description Agonist activity at PPARalpha (unknown origin) expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assa...				Bioorg Med Chem 16: 7117-27 (2008) Article DOI: 10.1016/j.bmc.2008.06.050 BindingDB Entry DOI: 10.7270/Q2K93792
					More data for this Ligand-Target Pair